Propolis changes the anticancer activity of temozolomide in U87MG human glioblastoma cell line
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چکیده
منابع مشابه
Propolis changes the anticancer activity of temozolomide in U87MG human glioblastoma cell line
BACKGROUND Propolis is a honey bee product which contains many active compounds, such as CAPE or chrysin, and has many beneficial activities. Recently, its anti-tumor properties have been discussed. We have tested whether the ethanolic extract of propolis (EEP) interferes with temozolomide (TMZ) to inhibit U87MG cell line growth. METHODS The U87MG glioblastoma cell line was exposed to TMZ (10...
متن کاملIn Vitro Radiosensitizing Effects of Temozolomide on U87MG Cell Lines of Human Glioblastoma Multiforme
Background: Glioma is the most common primary brain tumor with poor prognosis. Temozolomide (TMZ) has been used with irradiation (IR) to treat gliomas. The aim of the present study was to evaluate the cytotoxic and radiosensitizing effect of TMZ when combined with high-dose and high-dose rate of gamma irradiation in vitro.Methods: Two ‘U87MG’ cell lines and skin fibroblast were cultured and ass...
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Objective(s): Glioblastoma multiforme (GBM) is one of the most lethal forms of human cancer and temozolomide (TMZ) is currently part of the standard treatment for this disease. Combination therapy using natural substances can enhance the anti-cancer activity of TMZ. The purpose of this study was to evaluate the effect of TMZ in combination with thymoquinone (TQ) on human GBM cell line (U87MG). ...
متن کاملin vitro radiosensitizing effects of temozolomide on u87mg cell lines of human glioblastoma multiforme
background: glioma is the most common primary brain tumor with poor prognosis. temozolomide (tmz) has been used with irradiation (ir) to treat gliomas. the aim of the present study was to evaluate the cytotoxic and radiosensitizing effect of tmz when combined with high-dose and high-dose rate of gamma irradiation in vitro. methods: two ‘u87mg’ cell lines and skin fibroblast were cultured and as...
متن کاملIn Vitro Radiosensitizing Effects of Temozolomide on U87MG Cell Lines of Human Glioblastoma Multiforme
BACKGROUND Glioma is the most common primary brain tumor with poor prognosis. Temozolomide (TMZ) has been used with irradiation (IR) to treat gliomas. The aim of the present study was to evaluate the cytotoxic and radiosensitizing effect of TMZ when combined with high-dose and high-dose rate of gamma irradiation in vitro. METHODS Two 'U87MG' cell lines and skin fibroblast were cultured and as...
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ژورنال
عنوان ژورنال: BMC Complementary and Alternative Medicine
سال: 2013
ISSN: 1472-6882
DOI: 10.1186/1472-6882-13-50